Biofilms and microbial communities conceal a wealth of biological information – often difficult to access, but crucial for research and development. We use bioinformatic methods to make these structures visible, understandable and usable.

Bioinformatics for microorganisms

Microorganisms are everywhere – even in places where they can no longer be detected using conventional methods. Especially in complex structures such as biofilms, imaging methods quickly reach their limits. This is exactly where we come in: Using modern sequencing and analysis techniques, we extract DNA and RNA even from difficult, contaminated or unusual samples, thus providing a deep insight into microbial communities.

The key to this is bioinformatics. It helps us to systematically analyze the huge amounts of data generated during sequencing. With the help of special software and databases, we can find out which microorganisms are present in a sample, what they do there, how they work together – or whether their genetic information has changed due to external influences. Bioinformatics also allows us to better understand biological relationships, recognize patterns and even make predictions – for example, about how a system will develop under certain conditions.

Sequencing

Using DNA and RNA sequencing in combination with bioinformatic methods such as (meta-)genome analyses or transcriptome analyses, we identify the composition of microbial communities and analyze their genetic and functional properties. On this basis, we answer questions on biodiversity, gene expression, metabolic pathways and potential system boundaries.

Research opportunities

Whether in environmental microbiology, industrial process development or basic research – we offer comprehensive bioinformatic support in the analysis of microbial systems. Our work begins with sample preparation and sequencing and extends to the well-founded interpretation of complex biological data. You benefit from a broad range of methods that are individually tailored to your problem – for example, when processes run unexpectedly, biological systems are unstable or targeted optimizations are required.

Our research includes:

  • Taxonomic analyses to reliably determine the microbial composition of samples
  • Metabolomics for the identification of metabolic pathways and microbial functions
  • Mutation analyses to identify genetic changes caused by environmental or process conditions
  • Sequencing and evaluation from method selection to data-based interpretation
  • Comparative analysis to evaluate different samples or process conditions
  • Microbial material turnover to find out which factors influence biological processes and how processes can be specifically improved


We will be happy to advise you on your individual research project and work with you to develop a customized bioinformatics solution.

Our team

Prof. Dr. Johannes Gescher

Principal Investigator

Dr. Laura Philipp

Chief engineer

Dr. Jonas Lapp

Bioinformatician

How to reach us.

    What else we do.

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    With spraymatiq, we bring biofilms specifically to where they are needed. Our technology for sprayable biofilms enables rapid, controlled growth on different surfaces – scalable, customizable and ideal for robust applications in biotechnology, material protection and resource-saving process control.

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    Our technology combines microbial and chemical reaction steps to create a seamless and truly zero-waste production line for high performance polymers. Sustainability is at our hearts: We keep carbon bound and prevent the emission of greenhouse gases such as CO2, CH4 and N2O, unlike other sludge treatment processes.

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    Contact

    micromatiq

    Technische Universität Hamburg
    Institut für Technische Mikrobiologie V-7
    Kasernenstraße 12 (F)
    21073 Hamburg

    Copyright 2025